Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions.
Starting with an overview of the disease and its current political, financial and technical context, this "Milestones in Drug Therapy" volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.
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Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions.
Starting with an overview of the disease and its current political, financial and technical context, this "Milestones in Drug Therapy" volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.
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Imprint | Springer Basel |
Country of origin | Switzerland |
Series | Milestones in Drug Therapy |
Release date | February 2014 |
Availability | Expected to ship within 10 - 15 working days |
First published | 2012 |
Editors | Henry M. Staines, Sanjeev Krishna |
Dimensions | 235 x 155 x 20mm (L x W x T) |
Format | Paperback |
Pages | 318 |
Edition | 2012 ed. |
ISBN-13 | 978-3-03-480808-8 |
Barcode | 9783034808088 |
Categories | |
LSN | 3-03-480808-9 |